Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados Biol. Res. (1) BJMBR (1) Autor COUVE,EDUARDO (1) Fernandes,C.G. (1) Graça,D.L. (1) KRSULOVIC,JUAN (1) Pereira,L.A.V. (1) RONCAGLIOLO,MANUEL (1) Riet-Correa,G. (1) Mais... Palavra-chave Demyelination (2) Astrogliosis (1) Dysmyelination (1) Ethidium bromide (1) Myelin mutant (1) Optic nerve (1) Remyelination (1) Sciatic nerve (1) Taiep rat (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2002 (1) 1999 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Dysmyelination, demyelination and reactive astrogliosis in the optic nerve of the taiep rat Biol. Res. KRSULOVIC,JUAN; COUVE,EDUARDO; RONCAGLIOLO,MANUEL. Taiep is an autosomal recessive mutant rat that shows a highly hypomyelinated central nervous system (CNS). Oligodendrocytes accumulate microtubules (MTs) in association with endoplasmic reticulum (ER) membranes forming MT-ER complexes. The microtubular defect in oligodendrocytes, the abnormal formation of CNS myelin and the astrocytic reaction were characterized by immunocytochemical and ultrastructural methods during the first year of life. Optic nerves of both control and taiep rats were processed by the immunoperoxidase method using antibodies against tubulin, myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP). Taiep oligodendrocytes are strongly immunoreactive against tubulin, indicative of a significant accumulation of... Tipo: Journal article Palavras-chave: Myelin mutant; Taiep rat; Optic nerve; Dysmyelination; Demyelination; Astrogliosis. Ano: 1999 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97601999000400005 Ethidium bromide-induced demyelination of the sciatic nerve of adult Wistar rats BJMBR Riet-Correa,G.; Fernandes,C.G.; Pereira,L.A.V.; Graça,D.L.. Peripheral nerve ultrastructure was assessed after single or multiple local injections of the intercalating dye ethidium bromide. Thirty-four adult Wistar rats of both sexes were divided into five groups and maintained in a controlled environment with rat chow and water ad libitum throughout the experiment. The experimental animals were injected with 1 µl of 0.1% ethidium bromide in 0.9% saline into the central third of the left sciatic nerve 1 (group 1), 2 (group 2), 4 (group 3), 6 (group 4) or 8 (group 5) times. In groups 2 to 5 the injections were made at 28-day intervals. Control animals received the same amount of 0.9% saline. The animals were killed at different times after injection: group 1 at 7 days (2 rats) and 15 days (2 rats); for groups 2, 3,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Demyelination; Remyelination; Sciatic nerve; Ethidium bromide. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100014 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco